Distinguishing linear vs. non-linear integration in CA1 radial oblique dendrites: it’s about time

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Distinguishing Linear vs. Non-Linear Integration in CA1 Radial Oblique Dendrites: It’s about Time

It was recently shown that multiple excitatory inputs to CA1 pyramidal neuron dendrites must be activated nearly simultaneously to generate local dendritic spikes and supralinear responses at the soma; even slight input desynchronization prevented local spike initiation (Gasparini and Magee, 2006; Losonczy and Magee, 2006). This led to the conjecture that CA1 pyramidal neurons may only express ...

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ژورنال

عنوان ژورنال: Frontiers in Computational Neuroscience

سال: 2011

ISSN: 1662-5188

DOI: 10.3389/fncom.2011.00044